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Emamectin Benzoate

An Environmental Risk Assessment

Document format: pdf

Publisher: Scottish Environment Protection Agency

Creation date: June 1999

The severity of damage caused to farmed salmon due to infestation by the parasitic crustacean species Lepeophtheirus salmonis and Caligus elongatus (sea-lice) can be considerable and has led to the development of a number of potential chemical therapeutants. The semi-synthetic avermectin ivermectin is one of these and is known to be in use as an anti-sealice treatment in a number of countries including Canada, Ireland, and Chile. Avermectins act by binding to specific high-affinity binding sites resulting in increased membrane permeability to chloride ions and disruption of physiological processes. (15) Schering Plough Animal Health have identified a related semi-synthetic avermectin, emamectin benzoate which is active against juvenile, chalimus, motile pre-adult and adult sealice. It has been shown to be more effective against sealice but less toxic to salmon than ivermectin.

Key Words: Salmon • Scotland • Sea Lice • Medication • Parasite • Emamectin Benzoate • Risk Assessment • Environmental Impact